Profhilo vs Skin Boosters

Comparing bio-remodelling and hydration treatments for skin quality

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Skin boosters and Profhilo are both designed to improve skin quality from within, but they use different technologies and mechanisms. Understanding these differences helps you choose the right treatment for your skin goals.

Profhilo

Bio-remodelling with ultra-pure hyaluronic acid

Best For

  • Skin laxity
  • Crepey skin
  • Overall skin tightening
  • Neck and décolletage
  • Hands rejuvenation

Not Ideal For

  • Deep hydration only
  • Very young skin
  • Active acne

Lasts

6-12 months

Results

4-8 weeks

Sessions

2 sessions, 4 weeks apart

Price

From £300 per session

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SkinVive

Micro-droplet hyaluronic acid for hydration

Best For

  • Skin hydration
  • Smoothness
  • Glow enhancement
  • Fine lines
  • Cheeks and face

Not Ideal For

  • Significant laxity
  • Skin tightening
  • Volume loss

Lasts

6-9 months

Results

Immediate to 2 weeks

Sessions

1-2 sessions

Price

From £350 per session

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Polynucleotides

DNA fragments that stimulate cell regeneration

Best For

  • Skin regeneration
  • Under-eye rejuvenation
  • Scarring
  • Anti-ageing
  • Sensitive areas

Not Ideal For

  • Immediate results
  • Volume addition
  • Deep wrinkles

Lasts

6-12 months

Results

4-6 weeks

Sessions

2-3 sessions, 2-4 weeks apart

Price

From £250 per session

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Frequently Asked Questions

What's the main difference between Profhilo and other skin boosters?

Profhilo is a bio-remodelling treatment that spreads under the skin to stimulate collagen and elastin production, providing a lifting and tightening effect. Traditional skin boosters like SkinVive focus more on hydration and surface-level improvements.

Which is better for anti-ageing?

For significant anti-ageing benefits including skin tightening, Profhilo or Polynucleotides are typically more effective. SkinVive is excellent for maintaining hydrated, glowing skin but provides less structural improvement.

Can I combine these treatments?

Yes, these treatments can complement each other beautifully. For example, Profhilo for skin tightening combined with Polynucleotides for regeneration, or SkinVive for hydration maintenance between Profhilo courses.

Which has the least downtime?

All three have minimal downtime. SkinVive typically has the least visible injection marks. Profhilo and Polynucleotides may show small bumps at injection sites for 24-48 hours.

Which is best for the under-eye area?

Polynucleotides are particularly effective for the delicate under-eye area due to their regenerative properties. Profhilo can also be used around the eyes. SkinVive is not typically used in this area.

Doctor-Led
CQC Registered
Award-Recognised
Est. 2016

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Which is right for you?

The best treatment depends on your individual concerns, skin type, and goals. Here are some general considerations:

  • Choose Profhilo if your main concern is skin laxity and you want bio-remodelling with a tightening effect
  • Choose SkinVive if you primarily want improved hydration and a healthy glow
  • Choose Polynucleotides if you want cellular regeneration, particularly for delicate areas like under the eyes
  • These treatments can often be combined or alternated — your clinician will advise on sequencing

This is general guidance only — treatment suitability is always confirmed during a clinical consultation.

Doctor-led approach

Clinical governance

Reviewed by Dr Selena Langdon, Medical Director (GMC 6159259) — Last reviewed: February 2026

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